MMPredict consortium presents data on quality of life and cost effectiveness of risk at EHA 2019

MMPredict is a HORIZON 2020 project, which Myeloma Patients Europe (MPE) is involved in, aimed at clinically validating a personalised medicines tool that predicts the most effective treatment options for myeloma patients. As part of MMPredict, MPE has been involved in the development and dissemination of a survey  assessing the quality of life of European myeloma patients, particularly relating to currently available myeloma treatments and how side-effects impact upon them.

ASCO 2019 myeloma highlights

More than 40,000 people attended the American Society of Clinical Oncology (ASCO) Annual Meeting (ASCO 2019) which was held in Chicago from 31 May until 4 June. This meeting brings together oncology and haematology professionals from across the globe to discuss the latest scientific and treatment developments in the field. A number of myeloma topics were presented in this important scientific meeting. The most important updates are outlined below.

ASCO 2019 – Good results of the anti-BCMA Bispecific T cell engager (BiTE) immunotherapy in relapsed or refractory myeloma patients

  ASCO 2019, Chicago – New data of a first-in-human (FIH) phase I dose escalation study evaluating AMG 420, a B-cell maturation antigen (BCMA)-targeting BiTE molecule, were presented at the 55th Annual Meeting of the American Society of Clinical Oncology (ASCO) in Chicago. Data presented included updated investigational AMG 420 safety and efficacy results in patients with relapsed and/or refractory multiple myeloma (RRMM). BiTE technology is a targeted immuno-oncology platform that is designed to engage…

ASCO 2019 – Isatuximab plus pomalidomide and dexamethasone showed 40% reduction in the risk of disease progression for relapsed myeloma patients

  ASCO 2019, CHICAGO – Pivotal Phase 3 ICARIA-MM trial results demonstrated that isatuximab added to pomalidomide and dexamethasone (isatuximab combination therapy) showed statistically significant improvements compared to pomalidomide and dexamethasone (pom-dex) alone in patients with relapsed/refractory multiple myeloma (RRMM).

ASCO 2019 – Study shows that private insurance or higher regional incomes predict longer survival for myeloma patients

  ASCO 2019, CHICAGO – A new study presented at the American Society of Clinical Oncology (ASCO) Annual Meeting analysed demographic statistics from the National Cancer Database and identified multiple socio-economic factors, including private insurance, living in a regionally higher-income area and receiving treatment in certain practice settings as being associated with longer survival for mueloma patients. Furthermore, researchers found that neither race (black or white) nor gender had a significant impact on survival.